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期刊 Role of dendritic cells in MYD88-mediated immune recognition and osteoinduction ...
  • 作者 Zifan Zhao;Qin Zhao;Hu Chen;Fanfan Chen;Feifei Wang;Hua Tang;Haibin Xia;Yongsheng Zhou;and Yuchun Sun （ 1Center of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology＆National Center for Stomatology＆National Clinical Research Center for Oral Diseases＆National Engineering Research Center of Oral Biomaterials and Digital Medical Devices＆Beijing Key Laboratory of Digital Stomatology＆Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health＆NMPA Key Laboratory for Dental Materials；The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei- MOST)＆Key Laboratory of Oral Biomedicine, Ministry of Education, School＆Hospital of Stomatology, Wuhan University；Institute of Infection and Immunity, Medical Science and Technology Innovation Center, Shandong First Medical University＆Shandong Academy of Medical Sciences ）
  • 出处 International Journal of Oral Science 2023 第3期
浏览量12
期刊 Role of dendritic cells in MYD88-mediated immune recognition and osteoinduction ...
  • 作者 Zifan Zhao;Qin Zhao;Hu Chen;Fanfan Chen;Feifei Wang;Hua Tang;Haibin Xia;Yongsheng Zhou;and Yuchun Sun （ 1Center of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology＆National Center for Stomatology＆National Clinical Research Center for Oral Diseases＆National Engineering Research Center of Oral Biomaterials and Digital Medical Devices＆Beijing Key Laboratory of Digital Stomatology＆Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health＆NMPA Key Laboratory for Dental Materials；The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei- MOST)＆Key Laboratory of Oral Biomedicine, Ministry of Education, School＆Hospital of Stomatology, Wuhan University；Institute of Infection and Immunity, Medical Science and Technology Innovation Center, Shandong First Medical University＆Shandong Academy of Medical Sciences ）
  • 出处 International Journal of Oral Science 2023 第3期
浏览量10
期刊 Murine lung cDC1s inhibit memory Th2 cell generation by reducing CD62L memory p...
  • 作者 Jianguo Liu;Linqing Du;Shuying Yi;Lina Li;Yan Lin;Yanan Bi;Guangming Zhu;Xiuli Jing;Wengang Song;Hua Tang （ Affiliations 1 Department of Rheumatology and Autoimmunology, Shandong Provincial Key Laboratory for Rheumatic Disease and Translational Medicine, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, China. 2 School of Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China. 3 Institute of infection and immunity, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China. ）
  • 出处 Allergy 2022 Vol.77 No.11 P3467-3470
  • 关键词 Interleucina-12;Células Th2;Humanos;Camundongos;Animais;Pulmão;Memória Imunológica;
  • 摘要 GLO:1X5/01nov22:all15470-fig-0001.jpg PHOTO : 1 cDC1 depletion elevates memory potential of primed CD4+T cells to generate memory Th2 cells. Long-live
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期刊 Platelets fine-tune effector responses of naïve CD4 T cells via platelet factor ...
  • 作者 Yanan,Min;Long,Hao;Xinguang,Liu;Shuai,Tan;Hui,Song;Hao,Ni;Zi,Sheng;Natalie,Jooss;Xuena,Liu;Rickard E,Malmström;Yang,Sun;Jianguo,Liu;Hua,Tang;Hao,Zhang;Chunhong,Ma;Jun,Peng;Ming,Hou;Nailin,Li （ Department of Medicine-Solna '(1)' ; Cardiovascular Medicine Unit [2] ; J8:20 [3] ; Karolinska Institute [4] ; Karolinska University Hospital-Solna [5] ; 171 76 [6] ; Stockholm [7] ; Sweden. [8] ; Department of Hematology [9] ; Affiliated Hospital of Jining Medical University [10] ; Jining [11] ; China. [12] ; Department of Clinical Medicine [13] ; Shandong University of Traditional Chinese Medicine [14] ; Jinan [15] ; Department of General Surgery [16] ; Qilu Hospital of Shandong University [17] ; Department of Clinical Laboratory [18] ; Department of Rheumatology [19] ; Clinical Epidemiology Unit [20] ; Clinical Pharmacology Group [21] ; Department of Laboratory Medicine [22] ; Clinical Pharmacology [23] ; School of Basic Medicine [24] ; Department of Immunology and Shandong University-Karolinska Institutet Collaborative Laboratory [25] ; Shandong University Cheeloo Medical College [26] ; Shandong First Medical University and Shandong Academy of Medical Science [27] ; Institute of Immunology [28] ; Taian [29] ; Sweden. nailin.li@ki.se. [30] ）
  • 出处 Cellular and molecular life sciences : CMLS 2022 Vol.79 No.5 P247
  • 关键词 Effector cell responses;Na?ve CD4+ T cells;Platelet factor 4;Platelets;Platelet–T cell interactions;Transforming growth factor β;Type II TGFβ receptor;Type III TGFβ receptor;
  • 摘要 Platelets are an able regulator of CD4 T cell immunity. Herein, the mechanisms underlying platelet-regulated effector responses of naïve CD4 T cells
  • 收录

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    CPCI(ISTP)科技会议录索引(美)

    Scopus文摘索引数据库(荷)

浏览量11
期刊 烟酸促进小肠RORγtTregs稳态的维持
  • 作者 耿钰鑫;陈正涛;张钟允;董波;古惠文;李欣雨;贾凌云;王新;孙方园;唐华 （ 山东第一医科大学(山东省医学科学院)医学科技创新中心；山东第一医科大学(山东省医学科学院)实验动物学院(省实验动物中心)；山东第一医科大学第一附属医院(山东省千佛山医院) ）
  • 出处 山东第一医科大学(山东省医学科学院)学报 2022 第10期
  • 关键词 烟酸;小肠;RORγt+Treg;增殖;
  • 摘要 目的探索烟酸对小肠RORγtTregs稳态的影响。方法构建抗生素导致肠道共生菌群失调模型，使用流式细胞术检测小肠固有层RORγtTregs的比例；向含抗生素饮水中添加烟酸，用流式细胞术检测小肠固有层RORγtTregs、TH17细胞的比例以及Ki67蛋白的表达情况。结果研究结果显示，抗生素处理会导致
浏览量24
期刊 Ⅱ型固有淋巴细胞的研究进展
  • 作者 徐心悦;景秀丽;唐华 （ 山东第一医科大学(山东省医学科学院)临床与基础医学院山东济南；山东第一医科大学(山东省医学科学院)化学与制药工程学院山东济南；山东第一医科大学(山东省医学科学院)医学科技创新中心 ）
  • 出处 山东第一医科大学(山东省医学科学院)学报 2022 第9期
  • 关键词 Ⅱ型固有淋巴细胞;哮喘;肿瘤;代谢;
  • 摘要 Ⅱ型固有淋巴细胞是一群具有与Ⅱ型辅助性T细胞功能相似、能快速分泌Th2 型细胞因子的固有免疫细胞，在2 型免疫反应中具有重要作用。ILC2s可接收来自上皮细胞、基质细胞、神经细胞和其他免疫细胞的信号，进而调控下游效应细胞的功能，从而在肺、皮肤等屏障组织发挥重要的效应功能。本文将对ILC2s的分类、发
浏览量20
期刊 Immune profiles in mouse brain and testes infected by Zika virus with variable p...
  • 作者 Jingzhe Shang;Jingzhe Shang;Chunfeng Li;Chunfeng Li;Zhujia Jin;Zhujia Jin;Shulong Zu;Shulong Zu;Shulong Zu;Shulong Zu;Songjie Chen;Junlan Chen;Ziyi Chen;Ziyi Chen;Hua Tang;Cheng-Feng Qin;Qing Ye;Aiping Wu;Aiping Wu （ 1Institute of Systems Medicine, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing, China;2Suzhou Institute of Systems Medicine, Suzhou, China;3State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, China;4Institute for Immunity, Transplantation and Infection, School of Medicine, Stanford University, Stanford, CA, United States;5Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China;6Departments of Genetics, School of Medicine, Stanford University, Stanford, CA, United States;7State Key Laboratory Breeding Base of Basic Science of Stomatology, Ministry of Education, Hospital of Stomatology, Faculty of Medical Sciences, Wuhan University, Wuhan, China;8Institute of Immunology, Shandong First Medical University, Tai’an, China ）
  • 出处 Frontiers in Cellular and Infection Microbiology 2022 Vol.12
  • 关键词 immune profiles;ZIKV;variable pathogenicity;transcriptome;multi-organization;
  • 摘要 The Zika virus is responsible for neurological diseases such as microcephaly, Guillain-Barré syndrome, neuropathy, and myelitis in human adults and ch
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浏览量11
期刊 Flagellar Hooks and Hook Protein FlgE Participate in Host Microbe Interactions a...
  • 作者 Ying Shen;Lin Chen;Meixiang Wang;Dandan Lin;Zhongjie Liang;Peiqing Song;Qing Yuan;Hua Tang;Weihua Li;Kangmin Duan;Baiyan Liu;Ge Zhao;Yiqiang Wang （ MOH Key Lab of Thrombosis and Hemostasis, Collaborative Innovation Center of Hematology-Thrombosis and Hemostasis Group, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University Department of Oral Biology & Medical Microbiology, Faculty of Health Sciences, University of Manitoba Institute of Immunology, Taishan Medical University Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute Center for Systems Biology, Soochow University Molecular Microbiology Laboratory, Northwest University Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute Institute of Immunology, Taishan Medical University Institute of Basic Medical Sciences, National Center of Biomedical Analysis Department of Oral Biology & Medical Microbiology, Faculty of Health Sciences, University of Manitoba Key Laboratory of Internal Medicine, Hunan University of Traditional Chinese Medicine China Animal Health and Epidemiology Center MOH Key Lab of Thrombosis and Hemostasis, Collaborative Innovation Center of Hematology-Thrombosis and Hemostasis Group, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University ）
  • 出处 Scientific Reports 2017 Vol.7 No.1 P1-14
  • 摘要 Host-microbe interactions determine the outcome of host responses to commensal and pathogenic microbes. Previously, two epithelial cell-binding peptid
浏览量12
期刊 The Combinations Chitosan-PamCSK and Chitosan-Monophosphoryl Lipid A: Promising ...
  • 作者 Yongli Bi;Qingan Xu;Lingkai Su;Jiantao Xu;Zhongfang Liu;Ying Yang;Hua Tang;Yuhong Li;Mingwen Fan （ The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory for Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China;School of Medicine, Jianghan University, Wuhan, ChinaWuhan First Stomatological Hospital, Wuhan, China;Department of Endodontics and Key Laboratory for Oral Biomedical Research of Zhejiang Province, Affiliated Hospital of Stomatology, Medical College, Zhejiang University, Hangzhou, China;Taikang Tongji (Wuhan) Hospital, Wuhan, China;The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory for Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China;The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory for Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China;Institute of Immunology, Taishan Medical University, Taian, China;The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory for Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China;The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory for Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China;Georgia Institute of Technology School of Biological Sciences ）
  • 出处 Infection and Immunity 2019 Vol.87 No.12 Pe00651-19
  • 关键词 dental caries;PAc;adjuvant;chitosan;MPL;Pam3CSK4;
  • 摘要 We previously demonstrated that recombinant protein PAc could be administered as an anticaries vaccine. However, the relatively weak immunogenicity of
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期刊 Flagellar Hooks and Hook Protein FlgE Participate in Host Microbe Interactions a...
  • 作者 Ying Shen;Lin Chen;Meixiang Wang;Dandan Lin;Zhongjie Liang;Peiqing Song;Qing Yuan;Hua Tang;Weihua Li;Kangmin Duan;Baiyan Liu;Ge Zhao;Yiqiang Wang （ MOH Key Lab of Thrombosis and Hemostasis, Collaborative Innovation Center of Hematology-Thrombosis and Hemostasis Group, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, 215007, China. Department of Oral Biology &Medical Microbiology, Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, R3E 0W2, Canada. Molecular Microbiology Laboratory, Northwest University, Xi'an, 710069, China. Institute of Immunology, Taishan Medical University, Taian, 271000, China. Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, 266071, China. Center for Systems Biology, Soochow University, Suzhou, 215006, China. Institute of Basic Medical Sciences, National Center of Biomedical Analysis, Beijing, 100850, China. Key Laboratory of Internal Medicine, Hunan University of Traditional Chinese Medicine, Changsha, 410007, China. China Animal Health and Epidemiology Center, Qingdao, 266114, China. cathyge@163.com. MOH Key Lab of Thrombosis and Hemostasis, Collaborative Innovation Center of Hematology-Thrombosis and Hemostasis Group, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, 215007, China. yiqiangwang@suda.edu.cn. Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, 266071, China. yiqiangwang@suda.edu.cn. ）
  • 出处 Scientific reports 2017 Vol.7 No.1 P1433
  • 摘要 Host-microbe interactions determine the outcome of host responses to commensal and pathogenic microbes. Previously, two epithelial cell-binding peptid
  • 收录

    CPCI-S

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共22条记录 1/3 << 1 2 3 > >> GO
唐华，男，1968年12月出生，教授。2005年毕业于浙江大学获博士学位，2006-2010年在美国Emory大学做博士后研究，目前任泰山医学院免疫学研究所所长，被山东省人民政府授予“山东省引进海外高层次创新人才”和“泰山学者海外特聘专家”。
主要研究领域为细胞免疫学，尤其关注树突状细胞亚群对获得性免疫反应的调节。读博士期间与人合作，发现了新的调节性树突状细胞亚群，以共同第一作者将该工作以封面论文的形式发表于Nature Immunology。该文引起了国际同行的高度关注，Nature、Nature Review Immunology、Nature Immunology都作为重要研究作了推荐和评论。发现了免疫微环境促进造血前体细胞向树突状细胞定向分化并以第一作者发表于Blood。
在美国Emory Vaccine Center做博士后工作期间，发现位于皮肤真皮内的真皮树突状细胞亚群和嗜碱性粒细胞合作，共同诱导过敏免疫反应。以第一作者将该论文发表在2010年Nature Immunology，并被国际著名网站Faculty1000推荐为”必读”文章。同一时期，与人合作分别在Nature Immunology和Current Opinion of Immunology等杂志发表综述各一篇，与人合作的原创性成果的论文发表在Nature、Nature Immunology杂志上，系统阐述了树突状细胞及其亚群在调控获得性免疫反应中的作用。主持国家自然科学基金项目等课题。
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