张忠_山东第一医科大学机构知识库

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期刊 NIR laser-activated, indocyanine green-loaded bovine serum albumin nanoparticles...

作者 Kexin Zhang;Chenfei Zhang;Ying Li;Ting Li;Yansong Yin;Kaipeng Wang;Anqi Wang;Mingjia Zheng;Zhong Zhang;Haijun Wang （ ¹Hospital for Skin Diseases, Shandong First Medical University, Ji’nan 250022, China;²Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Ji’nan 250022, China;³The authors contributed equally to this work.;⁴School of Life Sciences, Shandong First Medical University and Shandong Academy of Medical Sciences, Tai’an 271016, China;⁵Collaborative Innovation Center for the Origin and Control of Emerging Infectious Diseases, Shandong First Medical University and Shandong Academy of Medical Sciences, Ji’nan 250117, China;⁶Shandong Second Medical University, Weifang 261053, China;⁷National Facility for Translational Medicine (Shanghai), Shanghai Jiao Tong University, Shanghai 200240, China ）
出处 International Journal of Pharmaceutics 2025 Vol.675 P125517
摘要 In this study, we proposed a novel application of an established material by developing ingestible nanoparticles made from bovine serum albumin loaded
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CPCI-S

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期刊 miR-276-3p在白纹伊蚊幼虫几丁质代谢调控中的作用研究

作者傅菁文;刘文娟;张忠;张瑞玲（ ¹山东第一医科大学(山东省医学科学院)临床与基础医学院；²山东第一医科大学(山东省医学科学院)实验动物学院(省实验动物中心) ）
出处中国媒介生物学及控制杂志 2023 第34卷第5期 P589-595
关键词白纹伊蚊;Agomir;Antagomir;miR-276-3p;饲喂;
摘要目的探讨miR-276-3p在白纹伊蚊幼虫几丁质代谢中的作用，为实现利用几丁质代谢相关miRNA防控白纹伊蚊提供新的靶标。方法合成miR-276-3p特异性模拟物agomir和抑制剂antagomir的壳聚糖纳米颗粒，通过饲喂法过表达或抑制白纹伊蚊幼虫体内miR-276-3p的表达。利用反转录实
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CSCD中国科学引文库(中科院)

中文核心期刊(北大)

CA化学文摘(美)

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期刊 Chromosome-level assembly of Culex pipiens molestus and improved reference genom...

作者 Wenjuan Liu;Peng Cheng;Sha An;Kexin Zhang;Maoqing Gong;Zhong Zhang;Ruiling Zhang （ Affiliations ¹ Collaborative Innovation Center for the Origin and Control of Emerging Infectious Diseases, Shandong First Medical University (Shandong Academy of Medical Sciences), Tai'an, China. ² School of Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Tai'an, China. ³ Shandong Institute of Parasitic Diseases, Shandong First Medical University (Shandong Academy of Medical Sciences), Jining, China. ）
出处 Molecular ecology resources 2022
关键词 Culex;Hi-C;PacBio sequencing;gene expansion.;
摘要 Culex pipiens molestus and Culex pipiens pallens are two distinct bioforms in the Culex pipiens complex that are important vectors of several pathogen
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CPCI-S

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Scopus文摘索引数据库(荷)

期刊 Molecular identification of the chitinase genes in Aedes albopictus and essentia...

作者 Sha An;Wenjuan Liu;Jingwen Fu;Zhong Zhang;Ruiling Zhang （ Affiliations ¹ Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250000, China. ² School of Clinical and Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan, 250117, China. ³ Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250000, China. vector0518@126.com. ⁴ School of Clinical and Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan, 250117, China. vector0518@126.com. ⁵ Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250000, China. zhangrl_06@126.com. ⁶ School of Clinical and Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan, 250117, China. zhangrl_06@126.com. ⁷ School of Laboratory Animal (Shandong Laboratory Animal Center), Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan, 250117, China. zhangrl_06@126.com. ）
出处 Parasites & vectors 2023 Vol.16 No.1 P120
关键词 Asian tiger mosquito;Chitin;Mosquito control.;
摘要 Background: Aedes albopictus is an increasingly serious threat in public health due to it is vector of multiple arboviruses that cause devastating hum
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CPCI-S

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Scopus文摘索引数据库(荷)

期刊 Whole-transcriptome profiling across different developmental stages of Aedes alb...

作者 Wenjuan Liu;Sha An;Peng Cheng;Kexin Zhang;Maoqing Gong;Zhong Zhang;Ruiling Zhang （ School of Clinical and Basic Medical Sciences, Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan, 250117, China School of Laboratory Animal (Shandong Laboratory Animal Center), Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan, 250117, China Shandong Institute of Parasitic Diseases, Shandong First Medical University (Shandong Academy of Medical Sciences), Jining, 272033, China ）
出处 Parasites & Vectors 2023 Vol.16 No.1 P1-13
关键词 ceRNA;ncRNA;Chitin;Mosquito;
摘要 Background The Asian tiger mosquito, Aedes albopictus , is one of the most invasive species and a vector of numerous arboviruses. The deleterious effe

浏览量11

期刊 Systematic identification and characterization of long noncoding RNAs during Ae...

作者 Wenjuan Liu;Peng Cheng;Kexin Zhang;Maoqing Gong;Zhong Zhang;Ruiling Zhang （ Collaborative Innovation Center for the Origin and Control of Emerging Infectious Diseases, Shandong First Medical University (Shandong Academy of Medical Sciences), Tai’an, China, School of Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Tai’an, China Collaborative Innovation Center for the Origin and Control of Emerging Infectious Diseases, Shandong First Medical University (Shandong Academy of Medical Sciences), Tai’an, China, Shandong Institute of Parasitic Diseases, Shandong First Medical University (Shandong Academy of Medical Sciences), Jining, China Collaborative Innovation Center for the Origin and Control of Emerging Infectious Diseases, Shandong First Medical University (Shandong Academy of Medical Sciences), Tai’an, China, School of Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Tai’an, China Collaborative Innovation Center for the Origin and Control of Emerging Infectious Diseases, Shandong First Medical University (Shandong Academy of Medical Sciences), Tai’an, China, Shandong Institute of Parasitic Diseases, Shandong First Medical University (Shandong Academy of Medical Sciences), Jining, China Collaborative Innovation Center for the Origin and Control of Emerging Infectious Diseases, Shandong First Medical University (Shandong Academy of Medical Sciences), Tai’an, China, School of Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Tai’an, China Collaborative Innovation Center for the Origin and Control of Emerging Infectious Diseases, Shandong First Medical University (Shandong Academy of Medical Sciences), Tai’an, China, School of Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Tai’an, China ）
出处 PLoS Neglected Tropical Diseases 2022 Vol.16 No.4 Pe0010245
关键词 Long non-coding RNA;Larvae;Metabolic processes;Eggs;Metabolic pathways;Pupae;RNA sequencing;Mosquitoes;
摘要 Background Aedes albopictus originated in the tropical forests of Southeast Asia and can currently be found on all continents. As one of the main arbo

期刊 Whole-transcriptome profiling across different developmental stages of Aedes alb...

作者 Wenjuan Liu;Sha An;Peng Cheng;Kexin Zhang;Maoqing Gong;Zhong Zhang;Ruiling Zhang （ Affiliations ¹ School of Clinical and Basic Medical Sciences, Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan, 250117, China. ² Shandong Institute of Parasitic Diseases, Shandong First Medical University (Shandong Academy of Medical Sciences), Jining, 272033, China. ³ Shandong Institute of Parasitic Diseases, Shandong First Medical University (Shandong Academy of Medical Sciences), Jining, 272033, China. meijiebiology@126.com. ⁴ School of Clinical and Basic Medical Sciences, Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan, 250117, China. vector0518@126.com. ⁵ School of Laboratory Animal (Shandong Laboratory Animal Center), Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan, 250117, China. vector0518@126.com. ⁶ School of Clinical and Basic Medical Sciences, Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan, 250117, China. zhangrl_06@126.com. ⁷ School of Laboratory Animal (Shandong Laboratory Animal Center), Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan, 250117, China. zhangrl_06@126.com. ）
出处 Parasites & vectors 2023 Vol.16 No.1 P33
关键词 Chitin;Mosquito;ceRNA;ncRNA.;
摘要 Background: The Asian tiger mosquito, Aedes albopictus, is one of the most invasive species and a vector of numerous arboviruses. The deleterious effe

期刊 Chromosome-level assembly of Culex pipiens molestus and improved reference genom...

作者 Wenjuan Liu;Peng Cheng;Sha An;Kexin Zhang;Maoqing Gong;Zhong Zhang;Ruiling Zhang （ Affiliations ¹ Collaborative Innovation Center for the Origin and Control of Emerging Infectious Diseases, Shandong First Medical University (Shandong Academy of Medical Sciences), Tai'an, China. ² School of Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Tai'an, China. ³ Shandong Institute of Parasitic Diseases, Shandong First Medical University (Shandong Academy of Medical Sciences), Jining, China. ）
出处 Molecular ecology resources Vol.23 No.2 P486-498
关键词 Culex;Hi-C;PacBio sequencing;gene expansion.;
摘要 Culex pipiens molestus and Culex pipiens pallens are two distinct bioforms in the Culex pipiens complex that are important vectors of several pathogen

期刊美洲大蠊和德国小蠊肠道内生真菌的分离鉴定及拮抗昆虫病原真菌的初步研究

作者乐倩倩;钮徐融;谢永辉;刘全俊;詹莜国;柯昌磊;李微杰;张倩;张心雨;张瑞玲;张忠;王志江（云南省烟草公司昆明市公司；山东第一医科大学(山东省医学科学院)基础医学院；云南农业大学植物保护学院）
出处江西农业学报 2022 第9期
关键词美洲大蠊;德国小蠊;肠道内生真菌;拮抗作用;昆虫病原真菌;
摘要采用传统昆虫内生菌分离及真菌培养方法并利用ITS扩增子测序法，对美洲大蠊和德国小蠊肠道内的可培养真菌进行了分离纯化及鉴定，利用平板对峙法观察分离出的肠道内生真菌对病原真菌的抑制情况，筛选出了对常见昆虫病原真菌具有一定有拮抗作用的菌株。结果表明，在美洲大蠊肠道中共分离得到8属12株真菌，其中丝孢酵母属
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统计源期刊(中信所)

浏览量33

期刊白纹伊蚊性别差异miRNA筛选及miRNA-mRNA调控网络分析

作者刘文娟;张可心;程鹏;张心雨;张倩;张忠;张瑞玲（山东第一医科大学基础医学院；山东第一医科大学寄生虫病防治研究所）
出处中国媒介生物学及控制杂志 2022 第33卷第2期 P191-200
关键词白纹伊蚊;性别分化;miRNA-mRNA;调控网络分析;
摘要目的研究雌、雄白纹伊蚊中差异表达的miRNA及其相对应的mRNA靶基因，进而探讨雌、雄白纹伊蚊miRNA-mRNA间的调控关系、预测关键基因的潜在功能，为阐明白纹伊蚊性别分化的调控机制积累资料。方法通过构建雌、雄白纹伊蚊miRNA文库和mRNA测序分析，分别得到雌、雄白纹伊蚊差异表达miRNA和m
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CSCD中国科学引文库(中科院)

中文核心期刊(北大)

CA化学文摘(美)

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学术成果
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张忠，男，1976年生，博士，副教授，泰山医学院病原生物学重点学科媒介生物学方向学术带头人，主要从事病原微生物学的教学与科研工作。山东省医学寄生虫学专业委员会委员，科研处副处长。2005年于浙江大学昆虫学专业博士毕业，至泰山医学院任教，主要从事媒介生物学相关研究。对昆虫生物学、生态学、生物防治及昆虫生理生化均有较深入研究。现主持国家自然科学基金面上项目“丽蝇蛹集金小蜂毒液蛋白抑制寄主免疫因子的分离纯化及基因克隆”和山东省中青年科学家奖励基金“蚊虫携带病原体检测用基因芯片的研制及应用”。发表学术研究论文10余篇,其中SCI源期刊论文1篇,参加国际学术会议4次,发表会议论文5篇;参加国内会议3次,发表会议论文3篇。