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作者

Pingping Zhang Fei Hua Xiaotao Yu Fen Qu Hui Xie Yong Zhao Xiaolong Zhao Lixia Jin Ailian Yu Baizhong Cui Lei Zhou

作者单位

Beijing Key Laboratory of Point-of-Care Testing for Bioemergency and Clinic (No. BZ0329), Beijing 100071, China Beijing Key Laboratory of Point-of-Care Testing for Bioemergency and Clinic (No. BZ0329), Beijing 100071, China Qinghai Institute for Endemic Disease Prevention and Control, Xining 811602, China Qinghai Institute for Endemic Disease Prevention and Control, Xining 811602, China Department of Etiology, Taishan Medical University, Taian 271000, China Qinghai Institute for Endemic Disease Prevention and Control, Xining 811602, China Laboratory of Analytical Microbiology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China Beijing Key Laboratory of Point-of-Care Testing for Bioemergency and Clinic (No. BZ0329), Beijing 100071, China Department of Etiology, Taishan Medical University, Taian 271000, China Clinical Diagnostic Center, 302nd Hospital of the People’s Liberation Army, Beijing 100039, China Qinghai Institute for Endemic Disease Prevention and Control, Xining 811602, China Clinical Diagnostic Center, 302nd Hospital of the People’s Liberation Army, Beijing 100039, China Qinghai Institute for Endemic Disease Prevention and Control, Xining 811602, China Laboratory of Analytical Microbiology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China Laboratory of Analytical Microbiology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China

刊名

Infectious Diseases and Translational Medicine

年份

2015

卷号

Vol.1 No.2

页码

58-60

关键词

Up-converting phosphor technology-based lateral-flow assay Point-of-care testing Isolation Yersinia pestis Decomposed viscera Surveillance

摘要

Dear Editor, Plague, a seriously infectious zoonotic disease caused by the Gram-negative bacterium Yersinia pestis, has claimed millions of lives during three major historic pandemics. Y. pestis, with a minimum infectious dose for mammals of less than 100 organisms (even less than 10 by the subcutaneous route), can proliferate in mammalian macrophages and migrate to internal organs within days. To date, with rodents as reservoirs and fleas as vectors, Y. pestis is widely and persistently distrib...更多

Dear Editor, Plague, a seriously infectious zoonotic disease caused by the Gram-negative bacterium Yersinia pestis, has claimed millions of lives during three major historic pandemics. Y. pestis, with a minimum infectious dose for mammals of less than 100 organisms (even less than 10 by the subcutaneous route), can proliferate in mammalian macrophages and migrate to internal organs within days. To date, with rodents as reservoirs and fleas as vectors, Y. pestis is widely and persistently distributed in natural foci on most continents (except Australia) and poses a high risk to humans. Therefore, surveillance and control of local plague hosts, including decomposed ones, are important in plague-endemic regions. Furthermore, inexpensive, convenient, and reliable point-of-care testing (POCT) is essential in resource-limited areas.收起

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