获取途径

作者

Y.L. ZHANG J.Y. WU X.C. WANG X.A. JING

作者单位

Taishan Medical University, China

刊名

International Journal of Cardiology

年份

2009

卷号

Vol.137 Suppl 1

页码

S93

ISSN

0031-6873

摘要

Objective Administration of ACE inhibitor (ACEI) and low sodium intake (LSI) increase plasma renin concentration. However, it is not clearly understood how ACEI and LSI alter both renin release and synthesis. The aim of this study was to determine the role of ACEI and LSI in both renin expression and release in hydronephrotic mice. Methods Balb/C mice (25–30 g) were anesthetized with sodium pentobarbitone (60 mg kg−1, i.p.) and the left ureter was ligated except sham-operated animals. Four weeks...更多

Objective Administration of ACE inhibitor (ACEI) and low sodium intake (LSI) increase plasma renin concentration. However, it is not clearly understood how ACEI and LSI alter both renin release and synthesis. The aim of this study was to determine the role of ACEI and LSI in both renin expression and release in hydronephrotic mice. Methods Balb/C mice (25–30 g) were anesthetized with sodium pentobarbitone (60 mg kg−1, i.p.) and the left ureter was ligated except sham-operated animals. Four weeks later, the left kidney became hydronephrotic.收起

学科

【SCI学科】CARDIAC & CARDIOVASCULAR SYSTEMS 【ESI学科】CLINICAL MEDICINE

影响因子

2016年:6.189;2015年:4.638;2014年:4.036;2013年:6.175;2012年:5.509

文献类型

期刊

浏览量

28