A novel height-adjustable nano hydroxyapatite/polyamide-66 vertebral body for reconstruction of thoracolumbar structural stability after spinal tumor resection.
Department of Orthopaedic Oncology Center, Changzheng Hospital, Second Military Medical University, Shanghai, China. Department of Orthopedics, Longhua Hospital, 725 South Wanping Road, Shanghai 200003, China. Department of Orthopaedic, People's Hospital of Shanghai Pudong New Area, Shanghai, 201200, China. Taishan Medical University, Tai'an, Shandong, 271016,China. Department of Orthopaedic, People's Hospital of Cixi, Zhejiang, 315300, China. Department of Orthopaedic Oncology Center, Changzheng Hospital, Second Military Medical University, Shanghai, China. Electronic address: xiaojr_spine@16com.
BACKGROUND: Reconstruction of thoracolumbar structural stability is a formidable challenge for spine surgeons after vertebral body tumor resection. Various disadvantages of the currently used expandable or non-expandable cages have limited their clinical applications. OBJECTIVE: To develop a novel prosthesis for clinical use and assess its preliminary clinical outcome in reconstruction of thoracolumbar structural stability after spinal tumor resection. METHODS: Based on the data obtained from a ...更多
BACKGROUND: Reconstruction of thoracolumbar structural stability is a formidable challenge for spine surgeons after vertebral body tumor resection. Various disadvantages of the currently used expandable or non-expandable cages have limited their clinical applications. OBJECTIVE: To develop a novel prosthesis for clinical use and assess its preliminary clinical outcome in reconstruction of thoracolumbar structural stability after spinal tumor resection. METHODS: Based on the data obtained from a retrospective analysis of the morphological characteristics of the thoracolumbar vertebrae and endplates in previously published articles, we modified the nano hydroxyapatite/polyamide-66 strut into a novel height adjustable vertebral body. A retrospective study was performed to include 7 patients who underwent reconstruction of thoracolumbar structural stability with this novel prosthesis from August 2016 to January 2017. RESULTS: A novel height adjustable vertebral body made of with two separate components with a 163-degree contact surface at each end was manufactured. The height adjustable range was 28mm to 37mm. No significant implant-related complications were observed in the process of operation. All patients had a significant reduction in pain with the VAS score decreasing from 7.9 to 4.0, and neurological improvement was assessed by the Frankel grading system after surgery. Postoperative radiographs and CT/MRI indicated that the operated segment was stability, the outcome of kyphosis correction was good, and no prosthesis subsidence or dislocation was observed. CONCLUSION: This novel prosthesis has many advantages in reconstruction of height, lordosis, and alignment after thoracolumbar spinal tumor resection and has a favorable prospect for clinical application.收起
发文期刊《A novel height-adjustable nano hydroxyapatite/polyamide-66 vertebral body for reconstruction of thoracolumbar structural stability after spinal tumor resection.》历年引证文献趋势图
