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作者

Bai, J Liu, Y Niu, GF Bai, LX Xu, XY Zhang, GZ Wang, LX

作者单位

Charles Sturt Univ, Sch Biomed Sci, Wagga Wagga, NSW, Australia   增强组织信息的名称     Charles Sturt University Taishan Med Univ, Dept Pharm, Liaocheng Peoples Hosp, Tai An, Shandong, Peoples R China   增强组织信息的名称     Taishan Medical University Taishan Med Univ, Liaocheng Clin Sch, Tai An, Shandong, Peoples R China   增强组织信息的名称     Taishan Medical University Taishan Med Univ, Dept Endocrinol, Liaocheng Peoples Hosp, Tai An, Shandong, Peoples R China   增强组织信息的名称     Taishan Medical University

刊名

BIOCHEMIA MEDICA

年份

2011

卷号

Vol.21 No.1

页码

65-69

关键词

METABOLIC SYNDROME RENAL-FUNCTION SERUM ADIPONECTIN MEN MELLITUS PROTEIN PUBERTY HUMANS GENDER SEX

分类号

572, 616

摘要

Introduction: This study was designed to investigate the relationship between serum adiponectin and testosterone in patients with type 2 diabetes. Materials and methods: Serum level of adiponectin and testosterone were prospectively measured in 65 patients with type 2 diabetes and in 20 healthy subjects. Testosterone was determined by the radio-immunoassay\' whereas adiponectin levels were determined by enzyme-linked immunosorbent assay (ELISA). Results:The average serum testosterone did not dif...更多

Introduction: This study was designed to investigate the relationship between serum adiponectin and testosterone in patients with type 2 diabetes. Materials and methods: Serum level of adiponectin and testosterone were prospectively measured in 65 patients with type 2 diabetes and in 20 healthy subjects. Testosterone was determined by the radio-immunoassay\' whereas adiponectin levels were determined by enzyme-linked immunosorbent assay (ELISA). Results:The average serum testosterone did not differ between the diabetes and the control group, but the average adiponectin in the diabetes group was lower (14.6 (14.2-15.0) vs. 24.3 (24.05-24.55) ng/mL, P = 0.001). In the diabetes group, the serum adiponectin level in patients with renal dysfunction (22.3 (21.5-23.1) ng/mL) was higher than in patients with no complications (12.1 (11.45-12.75) ng/mL) and than in patients with coronary artery disease (11.2 (10.25-12.15) ng/mL) (P 0.009). Univariate correlation analysis showed an inverse weak correlation between adiponectin and testosterone concentrations in male diabetic patients (r = -0.27, P = 0.009). There was no significant correlation between adiponectin and testosterone in female patients (r 0.05,P = 0.167). Conclusions: We conclude that patients with type 2 diabetes have lower serum adiponectin concentration than healthy individuals, and that there is a weak inverse correlation between adiponectin and testosterone serum concentrations in male diabetics.收起

学科

【SCI学科】MEDICAL LABORATORY TECHNOLOGY 【ESI学科】BIOLOGY & BIOCHEMISTRY

影响因子

2016年:2.934;2015年:3.051;2014年:2.667;2013年:2.4;2012年:1.873

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