The endocannabinoid system in regulation of cardiovascular functions

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作者单位: Institute of Atherosclerosis, Taishan Medical University, Taian Shandong 271000, China Institute of Materia Medica, Taishan Medical University, Taian Shandong 271000, China

关键词: Cannabinoid receptor Cardiovascular disease Endocannabinoid Heart Signaling pathway Vascular

摘要: The endocannabinoid exerts various cardiovascular effects such as vasorelaxation, lower blood pressure and negative inotropic effects via multiple signaling transduction by its receptor dependent and independent pathway. It is also involved in anti-inflammatory and endothelial-protecting effects. Therefore, the research on the pharmacological mechanism of the endocannabinoid system may play an important role in treatment of hypertension, atherosclerosis, myocardial ischemia reperfusion injury a...更多; The endocannabinoid exerts various cardiovascular effects such as vasorelaxation, lower blood pressure and negative inotropic effects via multiple signaling transduction by its receptor dependent and independent pathway. It is also involved in anti-inflammatory and endothelial-protecting effects. Therefore, the research on the pharmacological mechanism of the endocannabinoid system may play an important role in treatment of hypertension, atherosclerosis, myocardial ischemia reperfusion injury and heart failure.收起

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