Department of Radiology, Laigang Hospital Affiliated to Taishan Medical University, Laiwu, Shandong, Chinaa Department of Radiology, Qilu Hospital of Shandong University, Jinan, Shandong, China
Background: This study aims to subdivide BI-RADS-MRI Category 4 lesions and to evaluate the role of Fischer’s scoring system, apparent diffusion coefficient , and Fischer’s + ADC in differential diagnosis of breast lesions. Material/Methods: This study retrospectively analyzed the data of 143 patients , who were diagnosed by biopsy, and received dynamic contrast enhancement and diffusion-weighted imaging. The diagnostic efficacies of ADC, Fischer’s scoring system, and the Fischer’s + ADC were a...更多
Background: This study aims to subdivide BI-RADS-MRI Category 4 lesions and to evaluate the role of Fischer’s scoring system, apparent diffusion coefficient , and Fischer’s + ADC in differential diagnosis of breast lesions. Material/Methods: This study retrospectively analyzed the data of 143 patients , who were diagnosed by biopsy, and received dynamic contrast enhancement and diffusion-weighted imaging. The diagnostic efficacies of ADC, Fischer’s scoring system, and the Fischer’s + ADC were analyzed by the receiver operating characteristics curve. The area under the curve was calculated. Fischer’s scoring system and the Fischer’s + ADC were used to subdivide BI-RADS Category 4 breast lesions. Results: ADC value was negatively correlated with the tumor grade. The AUC of Fischer’s + ADC was significantly higher than that of ADC and Fischer’s . Scored by Fischer’s scoring system, Category 4 and 5 indicated a likely malignant threshold with sensitivity and specificity of 98.70% and 65.75%, respectively. Scored by the Fischer’s + ADC method, Category 4B and 4C indicated a likely malignant threshold with sensitivity of 97.40% and specificity of 82.19%. Kappa values were 0.63 , 0.65 , and 0.80 , respectively. The positive predictive value of BI-RADS 4A, 4B, and 4C were 7.69%, 52.38% and 89.29%, respectively. Conclusions: Fischer’s scoring system combined with ADC could reasonably subdivide Category 4 breast lesions with high specificity and sensitivity.收起
