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作者

Tian, Mimi Xiao, Lianxiang Jian, Nan Wei, Xinhong Liu, Shuwei Zhao, Hui Li, Guan Zhang, Shuai Liang, Wenjia Lin, Nan Lin, Xiangtao

作者单位

School of Medicine, Shandong University, Jinan China Shandong Medical Imaging Research Institute, Shandong University, Jinan China CT Department, Heze Municipal Hospital, Heze China Shandong Provincial Key Laboratory of Mental Disorders, Research Center for Sectional and Imaging Anatomy, Shandong University School of Medicine, Jinan China Department of Imaging, Shandong Provincial Western Hospital, Jinan China College of Radiology, Taishan Medical University, Tai'an China Department of Radiology, Shandong Provincial Hospital affiliated to Shandong University, Jinan China

刊名

Prenatal Diagnosis

年份

2019

卷号

Vol.39 No.10

页码

883-889

ISSN

0197-3851

摘要

Objective: This study aims to evaluate the accuracy of magnetic resonance imaging in diagnosing orofacial clefts and proposes specific signs for determining the type of cleft.Methods: Pregnant women in whom fetal facial malformations are suspected by ultrasonography underwent 1.5 T MRI. The accuracy of the prenatal US and MRI diagnosis was compared with the postnatal findings.Results: A total of 71 fetuses were included in the final analysis, which comprised of 35 cases of isolated cleft lip, ...更多

Objective: This study aims to evaluate the accuracy of magnetic resonance imaging in diagnosing orofacial clefts and proposes specific signs for determining the type of cleft.Methods: Pregnant women in whom fetal facial malformations are suspected by ultrasonography underwent 1.5 T MRI. The accuracy of the prenatal US and MRI diagnosis was compared with the postnatal findings.Results: A total of 71 fetuses were included in the final analysis, which comprised of 35 cases of isolated cleft lip, six cases of cleft lip and alveolus, 21 cases of cleft lip and palate, four cases of isolated cleft palate, and five normal fetuses. MRI was more sensitive than US . The accuracy of MRI for all types was 100%. Specific signs were proposed, indicating the normal hard, unilateral cleft, bilateral cleft, and cleft soft palates, respectively, which can facilitate the identification of different types of cleft palates.Conclusion: MRI can accurately diagnose the type of cleft based on typical signs, which can serve as a definite diagnostic modality and an effective supplement of US.收起

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