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作者单位

泰山医学院附属聊城市第二人民医院神经内科山东聊城252600 青岛大学附属医院老年医学科山东青岛266000

刊名

Progress in Modern Biomedicine

年份

2019

卷号

Vol.19 No.17

页码

3351-3355

ISSN

1673-6273

关键词

Acute cerebral infarction Blood lipid Chlamydia pneumoniae Elderly Hemodynamics Inflammatory factors 急性脑梗死 炎症因子 老年 肺炎衣原体 血流动力学 血脂

摘要

To research the correlation between Chlamydia pneumoniae infection and inflammatory factors, blood lipid levels and hemodynamics in elderly patients with acute cerebral infarction. The elderly patients with acute cerebral infarction and the same period health medical examiners who were selected as the research objects, and they were respectively as the observation group and the control group, the specific antibody A, specific antibody G and specific antibody M of CP in the two groups were mea...更多

To research the correlation between Chlamydia pneumoniae infection and inflammatory factors, blood lipid levels and hemodynamics in elderly patients with acute cerebral infarction. The elderly patients with acute cerebral infarction and the same period health medical examiners who were selected as the research objects, and they were respectively as the observation group and the control group, the specific antibody A, specific antibody G and specific antibody M of CP in the two groups were measured by Micro immunofluorescence test , and the positive rates of CP antibody in the two groups were compared. The observation group was divided into infected persons and uninfected persons according to the infection of CP, and the differences of inflammatory factors, blood lipid levels and hemodynamic indexes in the two groups were compared, the correlation between specific antibody positive and acute cerebral infarction was analyzed by logistic regression. The positive rates of CP antibody I gA and IgG in the observation group were significantly higher than those in the control group . The levels of tumor necrosis factor-琢, hypersensitive C reactive protein and interleukin-6 in the observation group were higher than those in the uninfected persons . CP infection was related to the occurrence and development of acute cerebral infarction in the elderly patients, the mechanism may be related to the release of inflammatory factors, the disturbance of blood lipid metabolism and the changes of hemodynamics, this leads to the formation of atherosclerotic plaques and thrombosis.收起

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