获取途径

作者

Y. He Y. Pang Z. Su Y. Zhou Y. Wang Y. Lu Y. Jiang X. Han L. Song L. Wang Z. Li X. Lv J. Yao X. Liu X. Zhou S. He Y. Zhang J. Li B. Wang L. Tang

作者单位

¹⁰Department of Clinical Spiritual Care, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China ³Department of Breast Cancer Radiotherapy, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, China ⁵Department of Medical Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China ⁷Department of Oncology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China ⁶Department of Breast Medical Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China ⁹Department of Integrated Chinese and Western Medicine, Shaanxi Provincial Cancer Hospital Affiliated to Medical College of Xi'an Jiaotong University, Xi'an, China ¹Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Psycho-oncology, Peking University Cancer Hospital & Institute, Beijing, China ¹²Department of Psycho-oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China ²These authors contributed equally to this work and are joint first authors. ¹¹Radiotherapy Center, Hubei Cancer Hospital, Wuhan, China ⁴The Fifth Department of Chemotherapy, The Affiliated Cancer Hospital of Guangxi Medical University, Guangxi Zhuang Autonomous Region, Nanning, China ⁸Department of Oncology, Xiamen Humanity Hospital, Xiamen, China

刊名

ESMO Open

年份

2022

卷号

Vol.7 No.6

页码

100595

ISSN

2059-7029

关键词

symptom burden psychological distress symptom management cancer

摘要

Background The management of physical symptoms and psychological distress of cancer patients is an important component of cancer care. The purpose of this study was to evaluate the symptom burden, psychological distress, and management status of hospitalized patients with advanced cancer in China and explore the potential influencing factors of undertreatment and non-treatment of symptoms. Patients and methods A total of 2930 hospitalized patients with advanced cancer were recruited from 10 ...更多

Background The management of physical symptoms and psychological distress of cancer patients is an important component of cancer care. The purpose of this study was to evaluate the symptom burden, psychological distress, and management status of hospitalized patients with advanced cancer in China and explore the potential influencing factors of undertreatment and non-treatment of symptoms. Patients and methods A total of 2930 hospitalized patients with advanced cancer were recruited from 10 centers all over China. Patient-reported MD Anderson Symptom Inventory, Hospital Anxiety and Depression Scale , and Patient Health Questionnaire-9 scales and symptom management–related information were collected and linked with the patient’s clinical data. The proportion of patients reporting moderate-to-severe symptoms and whether they were currently well managed were examined. Multivariable logistic regression models were applied to explore the factors correlated to undertreatment and non-treatment of symptoms. Results About 27% of patients reported over three MS symptoms, 16% reported over five, and 9% reported over seven. Regarding psychological distress, the prevalence of HADS-anxiety was 29% and that of PHQ-9 depression was 11%. Sixty-one percent of patients have at least one MS symptom without any treatment. Sex [odds ratio = 2.238, 95% confidence interval 1.502-3.336], Eastern Cooperative Oncology Group , and whether currently undergoing anticancer treatment are the main factors correlated with the undertreatment of symptoms. Age , sex , ECOG , whether currently undergoing anticancer treatment , and comorbidity are the main factors correlated with the non-treatment of symptoms. Conclusions This study shows that hospitalized patients with advanced cancer had a variety of physical and psychological symptoms but lacked adequate management and suggests that a complete symptom screening and management system is needed to deal with this complex problem.收起

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