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作者

Wen Wang Yuntao Long Chenghui Liu Yubin Qi

作者单位

³Department of Orthopedic Surgery, Jinan Seventh People's Hospital, No. 21 Gongye North Road, Jinan, Shandong Province, China ²Department of Orthopedic Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine, No.16766, Jingshi Road, Jinan, Shandong Province, China ¹Co-first author.

刊名

Asian Journal of Surgery

年份

2023

ISSN

1015-9584

摘要

Selection was practised for improved feed efficiency of mice on two alternative feeding regimes. In one set of lines animals were fed ad libitum, in the other set they were individually fed a fixed amount of feed which was not changed over generations. For each treatment, a pair of replicate lines were selected on efficiency from 3鈥5 weeks of age for 8 generations and another pair from 5鈥7 weeks for 7 generations. A control line was maintained for both E and L lines. In terminal generations ...更多

Selection was practised for improved feed efficiency of mice on two alternative feeding regimes. In one set of lines animals were fed ad libitum, in the other set they were individually fed a fixed amount of feed which was not changed over generations. For each treatment, a pair of replicate lines were selected on efficiency from 3鈥5 weeks of age for 8 generations and another pair from 5鈥7 weeks for 7 generations. A control line was maintained for both E and L lines. In terminal generations mice from each line were tested on each feeding regime, and carcasses of ad libitum fed mice were analysed.The realized heritability for efficiency averaged 13%, without much variation over treatments. In the E lines efficiency increased by about 18% of the control mean and in the L lines by about 60%, although absolute changes were small, and responses were similar on the two feeding regimes. Weights at the start of test decreased in the E lines and increased in the L lines; weights at the end of test increased in both.When tested on the alternative regimes, no interactions were detected for live weights, weight gains or efficiency; selection under fixed intake led to the same increase in appetite as did that under ad libitum.There were no interactions for carcass composition. Selection for efficiency led to an increase in fatness on both selection regimes and both weight ranges.收起

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