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作者

Wang, Zhichao Tan, Zicheng Qiu, Mengzhen Zhang, Longyang

作者单位

Department of Urology, Central Hospital Affiliated to Shandong First Medical University, Jinan, China Department of Urology, Jinan Central Hospital, Weifang Medical University, Jinan, China a Department of Urology, Jinan Central Hospital, Shandong University, Jinan, China

刊名

Current Urology

年份

2024

ISSN

1661-7649

关键词

Benign prostatic hyperplasia Holmium laser enucleation Meta-analysis Photoselective greenlight vaporization Reintervention

摘要

Background We compared the safety and efficacy of treating benign prostatic hyperplasia with photoselective greenlight vaporization versus holmium laser enucleation of the prostate . Methods Databases were searched for eligible studies evaluating HoLEP or PVP outcomes, published until May 2022. We analyzed the incidence of relative complications and postoperative outcomes, including the international prostate symptom score, maximum flow rate , postvoid residual urine volume, quality of life in...更多

Background We compared the safety and efficacy of treating benign prostatic hyperplasia with photoselective greenlight vaporization versus holmium laser enucleation of the prostate . Methods Databases were searched for eligible studies evaluating HoLEP or PVP outcomes, published until May 2022. We analyzed the incidence of relative complications and postoperative outcomes, including the international prostate symptom score, maximum flow rate , postvoid residual urine volume, quality of life index, and prostate-specific antigen levels. Results Eleven studies involving 4763 patients were included in this meta-analysis. The significant differences in postoperative Qmax at 1 month , 3 months , 6 months , and 12 months further confirmed unique advantage of HoLEP over PVP. We used forest plots to determine significant differences in the severe complication rates among patients in the PVP and HoLEP groups . Conclusions Holmium laser enucleation of the prostate and PVP showed comparable international prostate symptom scores, quality of life index, postvoid residual urine volumes, prostate-specific antigen levels, perioperative factors, and total complication rates. Compared with PVP, HoLEP had a greater Qmax 1 year postoperatively, decreased energy expenditure, and fewer high-grade complications. These results need to be verified in long-term follow-up studies with well-structured randomized controlled trials.收起

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