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作者

Wang, Luran Liu, Xueli Yang, Cuihong Yu, Yonghui Liu, Jing

作者单位

^aDepartment of Neonatology, Shandong Provincial Hospital, Shandong First Medical University, Jinan, 250014, China

刊名

Chinese Journal of Pediatrics

年份

2025

卷号

Vol.63 No.4

页码

387-393

ISSN

0578-1310

关键词

Death Infant, premature Intraventricular hemorrhage Risk factor

摘要

Objective To analyze the incidence and perinatal factors of death or severe intraventricular hemorrhage within the first week of life in preterm infants with gestational age minute Apgar score, incidence of hypothermia or early-onset sepsis, and the first arterial blood pH value were compared between the case and control groups of very preterm infants and extremely preterm infants. The χ² test and Wilcoxon rank-sum test were used for intergroup comparisons. A multivariable logistic regression ...更多

Objective To analyze the incidence and perinatal factors of death or severe intraventricular hemorrhage within the first week of life in preterm infants with gestational age minute Apgar score, incidence of hypothermia or early-onset sepsis, and the first arterial blood pH value were compared between the case and control groups of very preterm infants and extremely preterm infants. The χ² test and Wilcoxon rank-sum test were used for intergroup comparisons. A multivariable logistic regression model was used to analyze the factors for death or sIVH within the first week of life in very preterm and extremely preterm infants. Results Among the 8 903 preterm infants with gestational age minute Apgar score ≤7, early-onset sepsis, hypothermia at admission, and first arterial blood pH minute Apgar score ≤7 , hypothermia at admission and the first arterial blood pH <7.20 . Multiple births were an independent risk factor only for extremely preterm infants . Prenatal administration of a full course of antenatal corticosteroids was identified as a protective factor in very preterm and extremely preterm infants . Conclusions The incidence of death or sIVH within the first week of life remains high in preterm infants with gestational age <32 weeks. The smaller gestational age and lower birth weight, early-onset sepsis, birth asphyxia, hypothermia at admission, and a first arterial blood pH <7.20 were independent risk factors for death or sIVH within the first week of life in preterm infants with gestational age <32 weeks. A full course of antenatal corticosteroids significantly reduced the risk of these adverse outcomes.收起

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