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作者

Zhang, Shuai Li, Sha Xu, Tianqi Wang, Ximing

作者单位

^aDepartment of Radiology, Shandong Provincial Hospital Affiliated, Shandong First Medical University, Jinan, 250000, China

刊名

Chinese Journal of Radiology

年份

2025

卷号

Vol.59 No.2

页码

199-205

ISSN

1005-1201

关键词

Atherosclerosis Carotid artery Computed tomography angiography Intraplaque hemorrhage Perivascular adipose tissue

摘要

Objective To investigate the relationship between carotid intraplaque hemorrhage in CT angiography and perivascular fat density . Methods This study retrospectively analyzed 103 patients with carotid atherosclerosis, including 209 carotid plaques, who received carotid CTA and high-resolution magnetic resonance angiography in Shandong Provincial Hospital Affiliated to Shandong First Medical University from January 2018 to July 2023. According to the evaluation of IPH by MRI, the plaques were div...更多

Objective To investigate the relationship between carotid intraplaque hemorrhage in CT angiography and perivascular fat density . Methods This study retrospectively analyzed 103 patients with carotid atherosclerosis, including 209 carotid plaques, who received carotid CTA and high-resolution magnetic resonance angiography in Shandong Provincial Hospital Affiliated to Shandong First Medical University from January 2018 to July 2023. According to the evaluation of IPH by MRI, the plaques were divided into IPH group and non IPH group . CTA was used to evaluate the plaque characteristics and PFD. Univariate and multivariate logistic analysis was used to evaluate the relationship between PFD and IPH. The diagnostic efficacy of multiple features was performed by receiver operating characteristic curve analysis. Results Finally, 103 patients with 209 carotid plaques were collected. Multivariate logistic regression analysis showed that PFD still showed a significant association with IPH after adjusting for age, hyperlipidemia, degree of luminal stenosis, plaque calcification, maximum plaque thickness, and plaque density. The area under the curve values, sensitivity, specificity, and accuracy of combined PFD, maximum plaque thickness, and plaque density were 0.980, 88.24%, 98.39%, and 94.26%, respectively. Conclusion The changes of PFD in the carotid artery are closely related to the presence of carotid IPH in MRI and may become a new imaging indicator for high-risk plaque identification and cerebrovascular risk assessment.收起

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