Hailey-Hailey disease successfully treated with apremilast: two cases report and literature review

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作者单位: ^bShandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan, 250022, China ^aHospital for Skin Diseases, Shandong First Medical University, Jinan, 250022, China

摘要: Hailey-Hailey disease is a inheritary disease and there is currently no unified treatment standard. Apremilast, an oral small molecule phosphodiesterase 4 inhibitor, can significantly improve Hailey-Hailey disease according to foreign reports, but there are no relevant reports in China. This paper reported two patients with Hailey-Hailey disease who had a good response to apremilast in China reported for the first time, and relevant literature was reviewed.

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