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作者

Zhu, Jiankun Meng, Qian Kong, Kangbao Jin, Feng

作者单位

^bDepartment of Pediatrics, The Third Affiliated Hospital of Shandong First Medical University, Ji'nan, 250031, China ^aDepartment of Thoracic Surgery, Shandong Provincial Public Health Clinical Center, Shandong University, Ji'nan, 250100, China

刊名

Chinese Journal of Antituberculosis

年份

2025

卷号

Vol.47 No.3

页码

274-281

ISSN

1000-6621

关键词

Lung Mucormycosis Pneumonectomy Therapeutic uses

摘要

Objective: To explore the value of pneumonectomy in the treatment of pulmonary mucormycosis by reviewing relevant literature. Methods: A total of 10 patients were found having pulmonary mucormycosis treated with pneumonectomy through searching CNKI and PubMed database from 2004 to 2024. This study summarized characteristics of these 10 patients and analyzed indications and effectiveness of pneumonectomy in the treatment of pulmonary mucormycosis. Results: All 10 patients were deeply infected, 1 ...更多

Objective: To explore the value of pneumonectomy in the treatment of pulmonary mucormycosis by reviewing relevant literature. Methods: A total of 10 patients were found having pulmonary mucormycosis treated with pneumonectomy through searching CNKI and PubMed database from 2004 to 2024. This study summarized characteristics of these 10 patients and analyzed indications and effectiveness of pneumonectomy in the treatment of pulmonary mucormycosis. Results: All 10 patients were deeply infected, 1 case showed signs of disseminated infection in the remaining lungs, 8 out of the 10 patients had pulmonary artery invasion proved by postoperative pathological test, and 2 of them formed pulmonary artery pseudoaneurysm. Nine patients were found having main bronchial invasion, one of them involved carina, and one case had an astrobnopleural fistula. Among the 10 patients, 6 had diabetes mellitus, among whom 4 got long-term eure after surgery and 2 died during perioperative period. There were 3 patients with hematologic diseases and 1 patient with both hematologic diseases and diabetes mellitus, all of them died of hematologic diseases and related complications during the follow-up. Conclusion; Pulmonary mucormycosis has the characteristics of rapid progression and invasion of large vessels and central airways. In the presence of deep infection, involving pulmonary artery trunk and branches, invading main bronchus, etc., it can be used as indication for pneumonectomy. The underlying disease should be actively controlled, combined with antifungal drug therapy and intensive postoperative monitoring, which can reduce the oecurrence of postoperative complications.收起

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