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作者

Qian Dong, Rui Xia, Xue-Zhong Xing, Chang-Song Wang, Gang Ma, Hong-Zhi Wang, Biao Zhu, Jiang-Hong Zhao, Dong-Min Zhou, Li Zhang, Ming-Guang Huang, Rong-Xi Quan, Yong Ye, Guo-Xing Zhang, Zheng-Ying Jiang, Bing Huang, Shan-Ling Xu, Yun Xiao, Lin-Lin Zhang, Rui-Yun Lin, Shu-Liang Ma, Yu-An Qiu, Zhen Zheng, Ni Sun, Le-Wu Xian, Ji Li, Ming Zhang, Zhi-Jun Guo, Yong Tao, Xiang-Zhe Zhou, Wei Chen, Dao-Xie Wang, Ji-Yan Chi, Dong-Hao Wang, Kai-Zhong Liu

作者单位

Affiliations ¹ Department of Intensive Care Unit, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine, Chinese Academy of Sciences, Hangzhou 310000, Zhejiang Province, China. ² Department of Intensive Care Unit, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300000, China. ³ Department of Intensive Care Unit, Cancer Hospital Chinese Academy of Medical Sciences, Beijing 100021, China. ⁴ Department of Intensive Care Unit, Harbin Medical University Cancer Hospital, Harbin 150081, Heilongjiang Province, China. ⁵ Department of Intensive Care Unit, Sun Yat-sen University Cancer Center, Guangzhou 510060, Guangdong Province, China. ⁶ Department of Intensive Care Unit, Beijing Cancer Hospital, Beijing 100000, China. ⁷ Department of Intensive Care Unit, Fudan University Affiliated Shanghai Cancer Hospital, Shanghai 200000, China. ⁸ Department of Intensive Care Unit, Hunan Cancer Hospital, Changsha 410000, Hunan Province, China. ⁹ Department of Intensive Care Unit, Henan Cancer Hospital, Zhengzhou 450000, Henan Province, China. ¹⁰ Department of Intensive Care Unit, Hubei Cancer Hospital, Wuhan 430000, Hubei Province, China. ¹¹ Department of Intensive Care Unit, Shanxi Province Cancer Hospital, Taiyuan 030000, Shanxi Province, China. ¹² Department of Intensive Care Unit, Cancer Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830000, Xinjiang Uygur Autonomous Region, China. ¹³ Department of Intensive Care Unit, Fujian Cancer Hospital and Fujian Medical University Cancer Hospital, Fuzhou 350014, Fujian Province, China. ¹⁴ Department of Intensive Care Unit, Gaoxin District of Jilin Cancer Hospital, Changchun 130000, Jilin Province, China. ¹⁵ Department of Intensive Care Unit, Chongqing University Cancer Hospital, Chongqing 400000, China. ¹⁶ Department of Intensive Care Unit, Guangxi Medical University Affiliated Tumor Hospital, Nanning 530000, Guangxi Zhuang Autonomous Region, China. ¹⁷ Department of Intensive Care Unit, Sichuan Cancer Hospital and Institute, Chengdu 610041, Sichuan Province, China. ¹⁸ Department of Intensive Care Unit, Yunnan Cancer Hospital, Kunming 650000, Yunnan Province, China. ¹⁹ Department of Intensive Care Unit, Anhui Province Cancer Hospital, Hefei 230001, Anhui Province, China. ²⁰ Department of Intensive Care Unit, Cancer Hospital of Shantou University Medical College, Shantou 515000, Guangdong Province, China. ²¹ Department of Intensive Care Unit, Jiangsu Cancer Hospital, Nanjing 210000, Jiangsu Province, China. ²² Department of Intensive Care Unit, Jiangxi Provincial Tumor Hospital, Nanchang 330000, Jiangxi Province, China. ²³ Department of Intensive Care Unit, Liaoning Cancer Hospital and Institute, Shenyang 110000, Liaoning Province, China. ²⁴ Department of Intensive Care Unit, Huguang District of Jilin Cancer Hospital, Changchun 130000, Jilin Province, China. ²⁵ Department of Intensive Care Unit, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou 510000, Guangdong Province, China. ²⁶ Department of Intensive Care Unit, Hainan Cancer Hospital, Haikou 570000, Hainan Province, China. ²⁷ Department of Intensive Care Unit, Hangzhou Cancer Hospital, Hangzhou 310000, Zhejiang Province, China. ²⁸ Department of Intensive Care Unit, Shandong First Medical University Affiliated Tumor Hospital, Jinan 300000, Shandong Province, China. ²⁹ Department of Intensive Care Unit, Nantong Tumor Hospital, Nantong 256000, Jiangsu Province, China. ³⁰ Department of Intensive Care Unit, Gansu Provincial Cancer Hospital, Lanzhou 730000, Gansu Province, China. ³¹ Department of Intensive Care Unit, Beijing Shijitan Hospital Affiliated to Capital Medical University, Beijing 100000, China. ³² Department of Intensive Care Unit, Cancer Hospital of Zhengzhou, Zhengzhou 450000, Henan Province, China. ³³ Department of Intensive Care Unit, Tumor Hospital of Mudanjiang City, Mudanjiang 157000, Heilongjiang Province, China. ³⁴ Department of Intensive Care Unit, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine, Chinese Academy of Sciences, Hangzhou 310000, Zhejiang Province, China. liukaizhongicu@12 com.

刊名

World journal of gastrointestinal oncology

年份

2025

卷号

Vol.17 No.10

页码

108539

ISSN

1948-5204

关键词

Cancer-specialized hospitals Clinical records Colorectal cancer Intensive care unit Prognosis.

摘要

Background: Colorectal cancer is one of the most common cancers and CRC patients are among the most common intensive care unit admitted cancer patients. However, their prognosis and evaluation methods are rarely studied. Aim: To determine the short-term mortality outcome and identify the potential prognostic factors of CRC cancer patients admitted to the ICU. Methods: A multicenter cross-sectional study was performed from May 10, 2021 to July 10, 2021 at the ICU departments of 37 cancer specia...更多

Background: Colorectal cancer is one of the most common cancers and CRC patients are among the most common intensive care unit admitted cancer patients. However, their prognosis and evaluation methods are rarely studied. Aim: To determine the short-term mortality outcome and identify the potential prognostic factors of CRC cancer patients admitted to the ICU. Methods: A multicenter cross-sectional study was performed from May 10, 2021 to July 10, 2021 at the ICU departments of 37 cancer specialized hospitals in China, and included patients aged ≥ 14 years with ICU duration ≥ 24 hours. Clinical records of patients with a primary CRC diagnosis were reviewed. Patients were separated into groups according to 90-day survival. Characteristics between groups were compared. Univariate and multivariate regression tests were used to analyze the correlated factors of ICU outcomes. Predictive values of disease severity scores were assessed using receiver operating characteristic curve analysis. Results: In total, 189 CRC patients were included in the study. The 90-day mortality was 12.2%. Patients who died showed differences compared to patients who survived mostly in terms of disease severity and ICU complications. It appears that patients admitted to the ICU from a clinical ward due to emergencies may have a higher risk of mortality while surgical management was associated with better survival. In multivariate analysis, only chemotherapy, elective surgery and conventional oxygen therapy were identified as independently correlated with 90-day mortality. Sequential organ failure assessment and acute physiology and chronic health evaluation II scores had moderate accuracy in predicting short-term mortality. Conclusion: ICU admitted CRC patients appear to have low short-term mortality which requires further confirmation in prospective studies. The prognostic tools for these patients need further optimization.收起

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