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作者

Xiaowen Wang Huacheng Zhou Wenjian Xu Xiaohui Liu Jiaxiang Ni Guanglun Xie Changsheng Ma Senlin Hou Zhaoxia Xue Dong Yang Xiaoqiu Yang Tao Song Tao Sun Lingjie Xia Ruilin He Ke Ma Lijuan Lu Yongjin He Li Wan Guangzhao Liu

作者单位

²Department of Painology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China ¹⁴Department of Painology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China ⁹Department of Pain Medicine, Union Hospital of Huazhong Science and Technology University, Wuhan, China ¹⁰Department of Painology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China ¹²Department of Pain Medicine, Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China ¹⁸Department of Painology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China ¹⁵Department of Pain Medicine, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China ¹Department of Painology, The Second Hospital of Hebei Medical University, Shijiazhuang, China ¹¹Department of Painology, The First Hospital of China Medical University, Shenyang, China ¹⁷Department of Painology, Tianjin First Central Hospital, Tianjin, China ⁸Department of Painology, The First Hospital of Shanxi Medical University, Taiyuan, China ³Department of Radiology, Affiliated Hospital of Qingdao University, Qingdao, China ⁶Department of Human Anatomy, Hebei Medical University, Shijiazhuang, China ¹³Department of Pain Medicine, Henan Provincial People's Hospital, Zhengzhou, China ¹⁶Department of Painology, Nanjing Gulou Hospital, Nanjing, China ⁴Department of Painology, Xuanwu Hospital of Capital Medical University, Beijing, China ⁵Department of Pain & Rehabilitation and Palliative Medicine, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China ⁷Department of Bilio Pancreatic Endoscopic Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang, China

刊名

International Journal of Pain Research

年份

2026

卷号

Vol.2 No.1

页码

15-30

关键词

Celiac Plexus Splanchnic Nerve Nerve Block Neurolysis Alcohol Cancer Pain Expert Consensus

摘要

Celiac plexus block and neurolysis is an effective interventional technique for treating chronic upper abdominal pain. Currently, there are various CPB/N techniques, and there is an urgent need to develop an expert consensus to enable clinicians to correctly implement the CPB/N technique, improve efficacy, and reduce complications. A total of 20 medical experts were invited to participate in the writing of this expert consensus, including pain physicians, interventional radiologists, gastroente...更多

Celiac plexus block and neurolysis is an effective interventional technique for treating chronic upper abdominal pain. Currently, there are various CPB/N techniques, and there is an urgent need to develop an expert consensus to enable clinicians to correctly implement the CPB/N technique, improve efficacy, and reduce complications. A total of 20 medical experts were invited to participate in the writing of this expert consensus, including pain physicians, interventional radiologists, gastroenterologists/endoscopists, and anatomy professors. All experts are from Class A tertiary hospitals affiliated of medical universities in parts of China. Except for the anatomy professors, all experts are engaged in the clinical practice of CPB/N surgery and are familiar with indications, surgical procedures, and complication management. Chinese and English literatures related to CPB/N from January 2008 to October 2025 were retrieved to evaluate the recommendation levels. Each expert made multiple revisions to the initial draft of the expert consensus and voted on the classification levels with significant disagreements. This expert consensus reviews the anatomical characteristics of the celiac plexus, summarizes the indications and contraindications for the clinical implementation of CPB/N, describes in detail the technical methods of CPB/N via different approaches, expounds on the drugs and dosages for CPB and CPN, and depicts the clinical manifestations, management, and prevention of complications. Based on the current domestic practice of CPB/N and literature reports, the recommended grades for CPB/N are proposed. We recommend the posterior retrocrural/antecrural approach under CT guidance and EUS-guided CPB/N technique due to their high success rate and low risk. We do not recommend the approach with potential iatrogenic risks, such as transarterial puncture. The incidence of CPB/N complications is very low, and some complications are temporary. Performing CPB/N under imaging guidance can prevent the occurrence of serious complications such as nerve injury and bleeding.收起

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