Objective: To explore the risk factors for major adverse cardiovascular events in patients with type 2 diabetes mellitus in rural areas. Methods: A real-world observational study was conducted, enrolling 488 rural T2DM patients. Baseline data were collected, and participants were followed for 2 years. Multivariate Cox regression analysis was performed to identify risk factors for MACE. Results: During the 2-year follow-up, 51.64% of patients developed MACE, with a recurrence rate of 73.56% in ...更多
Objective: To explore the risk factors for major adverse cardiovascular events in patients with type 2 diabetes mellitus in rural areas. Methods: A real-world observational study was conducted, enrolling 488 rural T2DM patients. Baseline data were collected, and participants were followed for 2 years. Multivariate Cox regression analysis was performed to identify risk factors for MACE. Results: During the 2-year follow-up, 51.64% of patients developed MACE, with a recurrence rate of 73.56% in those with a baseline history of MACE and an incidence rate of 39.49% in those without prior MACE. Multivariate analysis revealed that disease duration, glycated hemoglobin , low-density lipoprotein cholesterol compliance rate, homocysteine , urinary microalbumin , urinary albumin-to-creatinine ratio , and fasting insulin were independent risk factors for MACE. Novel hypoglycemic agents exhibited low utilization rates and were associated with an increased risk of MACE. Conclusion: Prolonged T2DM duration, poor glycemic control, and renal impairment are critical risk factors for MACE. Primary hospitals should promote the use of hypoglycemic agents with cardiovascular protective effects to mitigate MACE risk.收起
