获取途径

作者

Zexing Song Yifei Wang Rusong Meng Zhenyuan Chen Yaoying Gao Xiangjie An Jing Yang Yue Yin Liuqing Chen Linlin Xin Ying Xia Juan Tao Liu Yang

作者单位

com. ⁹ Hubei Engineering Research Center of Skin Disease Theranostics and Health, Wuhan, 430022, Hubei, China. bengpao82@16 Hospital, Wuhan, 430030, Hubei, China. ⁶ Department of Dermatology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong, China. ⁷ Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China. ⁸ Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan, 430022, Hubei, China. bengpao82@16 Affiliations ¹ Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan, 430022, Hubei, China. ² Hubei Engineering Research Center of Skin Disease Theranostics and Health, Wuhan, 430022, Hubei, China. ³ Department of Dermatology, Specialty Medical Center of the Air Force, Chinese People's Liberation Army, Beijing, 100142, China. ⁴ Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China. ⁵ Department of Dermatology, Wuhan No. com.

刊名

Archives of dermatological research

ISSN

1432-069X

关键词

Age Anatomic location Basal cell carcinoma Dermoscopy Morphology.

摘要

Basal cell carcinoma is rare in young individuals and reported to possess different pathogenetic, clinical and histological features from late-onset BCC. However, the dermoscopic variability of BCC according to age of onset has not been investigated. Anatomic location was revealed to be associated with dermoscopic variation of BCC in Western population, but whether it applies to Asian population remains unknown. We evaluated the clinical and dermoscopic features of 448 BCCs and compared each fe...更多

Basal cell carcinoma is rare in young individuals and reported to possess different pathogenetic, clinical and histological features from late-onset BCC. However, the dermoscopic variability of BCC according to age of onset has not been investigated. Anatomic location was revealed to be associated with dermoscopic variation of BCC in Western population, but whether it applies to Asian population remains unknown. We evaluated the clinical and dermoscopic features of 448 BCCs and compared each feature by age of onset and anatomic location. Early-onset BCCs occurred more frequently on non-sun-exposed sites and were less pigmented than late-onset BCCs . Blue-gray globules and no vessels were independently associated with early-onset BCCs, whereas arborizing telangiectasia , large blue-gray ovoid nests and ulceration were less common in early-onset BCCs. Scalp BCCs were significantly more pigmented than BCCs located elsewhere . Superficial subtype , spoke-wheel areas , superficial erosions and polymorph vessels were independently associated with trunk BCCs, whereas nodular subtype and arborizing telangiectasias with BCCs on face and neck. Our findings suggest that age of onset and anatomic location are independent factors affecting the dermoscopic appearance of BCC.收起

文献类型

期刊

浏览量

16