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作者

Mei-Huan Wang Xiao Liu Qian Wang Hua-Wei Zhang

作者单位

²Department of Ultrasound, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China ¹Department of Ultrasound, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China

刊名

Frontiers in Endocrinology

年份

2022

卷号

Vol.13

页码

952113

ISSN

1664-2392

关键词

papillary thyroid carcinoma thyroid nodule thermal ablation radiofrequency ablation microwave ablation laser ablation

摘要

BackgroundPapillary thyroid cancer is the most common thyroid tumor, and early diagnosis and treatment can effectively improve prognosis. Many controversies surround the treatment method of T1N0M0 PTC. Recently, thermal ablation has shown some benefits in the treatment of PTC patients, but the safety and efficacy of its treatment remain controversial. This article performs a meta-analysis of TA in patients with T1aN0M0 and T1bN0M0 PTC.MethodsThe PubMed, Embase, Web of Science, and Cochrane Lib...更多

BackgroundPapillary thyroid cancer is the most common thyroid tumor, and early diagnosis and treatment can effectively improve prognosis. Many controversies surround the treatment method of T1N0M0 PTC. Recently, thermal ablation has shown some benefits in the treatment of PTC patients, but the safety and efficacy of its treatment remain controversial. This article performs a meta-analysis of TA in patients with T1aN0M0 and T1bN0M0 PTC.MethodsThe PubMed, Embase, Web of Science, and Cochrane Library databases were systematically searched for retrospective or prospective studies of TA for treating patients with T1N0M0 PTC from the database establishment to May 1, 2022. Data on volume reduction rate , disease progress, and complication rate were collected. In addition, a meta-analysis was performed using the Stata 12.0 and Review Manager 5.3.ResultsA total of 9 eligible studies were included. Our study demonstrated the effectiveness of VRR and disease progress. The VRR was reduced after 3 months , 6 months , 12 months , and 24 months . The disease progress was 1.9% . Safety is justified by the complication rate, which was 6.5% . Pain and hoarseness were the most common complications, and no life-threatening complications were reported. Egger’s test demonstrated that publication bias was acceptable.ConclusionsTA is an effective and safe method for managing T1aN0M0 and T1bN0M0 papillary thyroid nodules.收起

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