Research Progress of Zoledronic Acid in the Treatment of Osteoarthritis

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摘要: Osteoarthritis is a clinically common chronic autoimmune disease that progresses gradually. OA is not an autoimmune disease, but a degenerative disease, which can easily lead to joint pain, limited movement, etc., with a relatively long course of disease and slow progress, and cannot be cured clinically. With the gradual progress of OA, the degree of joint damage is aggravated, and the movement is limited, leading to muscle atrophy, and finally joint deformation, which seriously af-fects daily ...更多; Osteoarthritis is a clinically common chronic autoimmune disease that progresses gradually. OA is not an autoimmune disease, but a degenerative disease, which can easily lead to joint pain, limited movement, etc., with a relatively long course of disease and slow progress, and cannot be cured clinically. With the gradual progress of OA, the degree of joint damage is aggravated, and the movement is limited, leading to muscle atrophy, and finally joint deformation, which seriously af-fects daily life. Zoledronic acid is a diphosphonate, which has the effect of relieving pain and inhib-iting bone resorption. It is often used in the treatment of osteoporosis, knee OA, osteitis deforming, hypercalcemia and other diseases, and the effect is significant. Based on this, this study reviews the research progress of zoledronic acid in the treatment of OA.收起

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