专家学者_山东第一医科大学机构知识库
专家学者_山东第一医科大学机构知识库
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全部字段 题名 作者 关键词 摘要 学术ID
A FRET-based ratiometric fluorescent probe for detection of intrinsically generated SO2 derivatives in mitochondria.
作者
Song, Guangle Liu, Aikun Jiang, Hongli Ji, Ruixue Dong, Jian Ge, Yanqing
作者单位
School of Chemistry and Pharmaceutical Engineering, Taishan Medical University, Taian, Shandong, 271016, PR China
刊名
Analytica Chimica Acta
年份
2019
卷号
Vol.1053
页码
148-154
ISSN
0003-2670
关键词
Cell imaging Hemicyanine Mitochondria Pyrido[1,2-a]benzimidazole Water
摘要
A mitochondria-targeted ratiometric fluorescent probe based on hemicyanine and pyrido[1,2-a]benzimidazole was presented. It shows high sensitivity and selectivity toward SO 2 in pure water. The limit of detection was as low as 26.7 nM, which is superior to most reported probes. Most importantly, the probe was successfully used for fluorescence imaging of endogenous bisulfite in mitochondria in Glioma cells.
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