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作者

Qian,Yu Chenyu,Liu Biagio,Collura Rakesh,Navuluri Mikin,Patel Zhiyong,Yu Osman,Ahmed

作者单位

School of Medicine ^[10] University of Arizona Medical Center ^[22] Department of General Surgery Shandong Province Miramar ^[14] Florida ' Chicago ^[19] Washington DC ^[12] George Washington University ^[11] AZ ^[24] Shandong Cancer Hospital and Institute ^' Tucson ^[23] Department of Radiology ^[21] China. drzhiyongyu65@gmail.com. ^[25] USA. China. Cleveland Clinic Florida IL ^[20] Shandong First Medical University and Shandong Academy of Medical Sciences FL ^[15] University of Chicago ^[18] Ross University ^[13] Department of Radiology ^[17] Division of Interventional Radiology ^[16] Jinan City

刊名

World journal of emergency surgery : WJES. [electronic resource]

年份

2021

卷号

Vol.16 No.1

页码

29

关键词

Embolization Gastrointestinal bleeding Interventional radiology Ulcer

摘要

To conduct a meta-analysis to assess the safety and efficacy of prophylactic transcatheter arterial embolization for the treatment of high-risk bleeding peptic ulcers after achieving endoscopic hemostasis. PubMed and Cochrane Library were queried for full-text articles published up to December 2019. The following keywords were used: 'prophylactic embolization', 'supplement embolization', 'gastrointestinal bleeding', and 'ulcer bleeding'. High-risk ulcers were defined based on endoscopic finding...更多

To conduct a meta-analysis to assess the safety and efficacy of prophylactic transcatheter arterial embolization for the treatment of high-risk bleeding peptic ulcers after achieving endoscopic hemostasis. PubMed and Cochrane Library were queried for full-text articles published up to December 2019. The following keywords were used: 'prophylactic embolization', 'supplement embolization', 'gastrointestinal bleeding', and 'ulcer bleeding'. High-risk ulcers were defined based on endoscopic findings and/or clinical presentation . Only comparative studies investigating PTAE versus conservative treatment after achieving endoscopic hemostasis were included. Baseline study characteristics, rebleeding rate, need for surgery, mortality, and PTAE-related complication rates were investigated. Quantitative analyses were performed with Stata 15.1. Among the five included original studies, a total of 265 patients received PTAE and 617 were managed conservatively after endoscopy. The rebleeding rate and mortality of patients from the PTAE group were lower than the control group. PTAE also reduced the cumulative need for future surgical intervention . The PTAE-related major and minor events were 0.75% and 14.4%, respectively. PTAE had therapeutic potentials in reducing rebleeding risk, need for surgical intervention, and morality in high-risk peptic ulcers after achieving endoscopic hemostasis. The embolization-associated adverse events were minimal. Future studies should aim to increase the sample size and resources for performing endovascular interventions.收起

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