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作者

Yu, A., Cai, X., Zhang, Z., Shi, H., Liu, D., Zhang, P., Fu, Z.Email Author View Correspondence

作者单位

a Department of Pain Management, Shandong Provincial Hospital, Shandong University Shandong Province, 324 Jingwu Road, Jinan, Shandong Province, 250021, China Department of Anesthesiology, Affiliated Hospital of Taishan Medical, University Shandong Province, Taian, China Department of Anesthesiology, Liaocheng People's Hospital Shandong Province, Liaocheng, China

刊名

Acta Anaesthesiologica Scandinavica

年份

2015

卷号

Vol.59 No.1

页码

115-122

ISSN

0001-5172;1399-6576

关键词

EMTREE drug terms nicotine opiate paracetamol sufentanil tramadol narcotic analgesic agent EMTREE medical terms adult Article cancer surgery case control study comparative study controlled study coughing esophagus carcinoma Fagerstrom Test for Nicotine Dependence human loading drug dose lobectomy major clinical study male nausea observational study operation duration pain assessment pain intensity patient controlled analgesia postoperative analgesia postoperative complication postoperative nausea and vomiting postoperative pain radical resection respiration depression retrospective study sedation smoking surgical patient thorax surgery tobacco dependence vomiting aged female middle aged Pain, Postoperative pathophysiology tobacco dependence MeSH Adult Aged Analgesics, Opioid Case-Control Studies Female Humans Male Middle Aged Pain, Postoperative Retrospective Studies Thoracic Surgical Procedures Tobacco Use Disorder

分类号

617.96

摘要

Background This retrospective study investigated the effect of nicotine dependence on required postoperative opioid administration in patients undergoing thoracic surgery. Methods The subjects consisted of 215 male patients who underwent thoracic surgery and received postoperative patient-controlled intravenous analgesia. Evaluations of nicotine dependence were based on results of Fagerstrom Test of Nicotine Dependence questionnaires. Smokers were categorized as low-nicotine dependent or hig...更多

Background This retrospective study investigated the effect of nicotine dependence on required postoperative opioid administration in patients undergoing thoracic surgery. Methods The subjects consisted of 215 male patients who underwent thoracic surgery and received postoperative patient-controlled intravenous analgesia. Evaluations of nicotine dependence were based on results of Fagerstrom Test of Nicotine Dependence questionnaires. Smokers were categorized as low-nicotine dependent or highly-nicotine dependent with FTND scores < 6 or ≥ 6, respectively. Pain intensity was assessed every 2 h after surgery, using the numerical rating scale . The cumulative amount of self-administered sufentanil at 24 and 48 h after surgery was recorded. Results There were no significant differences in baseline clinical characteristics among the nonsmoker , LD, and HD groups. The NRS scores and total amount of self-administered sufentanil were significantly higher in the HD and LD groups compared with the NS group, and were significantly higher in the HD group than in the LD group. The FTND scores positively correlated with the cumulative quantity of sufentanil. Postoperative complications such as nausea and vomiting, sedation, and respiratory depression did not significantly differ among the groups. Conclusions Smokers had more severe postoperative pain and required a higher quantity of postoperative opioid than nonsmokers. With increasing nicotine dependence, postoperative pain severity and postoperative opioid requirement increased.收起

学科

【SCI学科】ANESTHESIOLOGY 【ESI学科】CLINICAL MEDICINE

影响因子

2018年:2.228;2017年:2.27;2016年:2.438;2015年:2.049;2014年:2.322

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期刊

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