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作者单位

广西壮族自治区人民医院肝胆胰脾外科, 南宁53002 山东省肿瘤防治研究院 山东省肿瘤医院山东第一医科大学山东省医学科学院肝胆外科, 济南25011

刊名

Chinese Journal of Oncology / Zhonghua Zhongliu Zazhi

年份

2021

卷号

Vol.43 No.6

页码

635-637

ISSN

0253-3766

关键词

Hepatocellular neoplasms Operation Recurrence 复发 手术 肝肿瘤 Hepatocellular neoplasms Operation Recurrence

摘要

Hepatocellular carcinoma owns the high morbidity and mortality rates. Surgical resection is still the major pathway for the longer survival of HCC patients. Postoperative recurrence and metastasis have become the key impairment of prognosis of HCC patients. The relationship between tumor recurrence and surgical manner underwent by HCC patients is complicated and multiple factors are included. When the liver tumor was pressured during operation, tumor cells could be squeezed into blood flow via ...更多

Hepatocellular carcinoma owns the high morbidity and mortality rates. Surgical resection is still the major pathway for the longer survival of HCC patients. Postoperative recurrence and metastasis have become the key impairment of prognosis of HCC patients. The relationship between tumor recurrence and surgical manner underwent by HCC patients is complicated and multiple factors are included. When the liver tumor was pressured during operation, tumor cells could be squeezed into blood flow via the broken vessels, which resulted in tumor metastasis. Besides, ischemia-reperfusion injury induced by Pringle maneuver during the liver blood blockade resulted in the immune destruction of liver and induced tumor recurrence.The destruction of physical barriers consisted of interstitial cells and normal liver cells was also a key factor for tumor recurrence. This paper summarizes the possible relationship between postoperative recurrence and surgical manner in HCC patients to provide the preventive suggestions for the postoperative recurrence of HCC patients.收起

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