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作者

Feng-Xia Dong, Hong-Rong Fei, Xue-Qin Hou, Lu-Yu Ma

作者单位

Affiliation ¹ College of Pharmacy & Institute of Materia Medica，Shandong First Medical University & Shandong Academy of Medical Sciences，Jinan 250117，China.

刊名

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae

年份

2026

卷号

Vol.48 No.4

页码

733-741

ISSN

1000-503X

关键词

breast cancer mechanism of action phytoestrogen prevention and treatment traditional Chinese medicine.

摘要

Phytoestrogens are a class of natural compounds existing in plants，with their chemical structures similar to that of the endogenous estrogen 17β-estradiol in mammals.They can exert estrogenic or anti-estrogenic biological effects by binding to estrogen receptors，and have a wide range of effects on diseases caused by estrogen disorders in the body.Recent studies have discovered that phytoestrogens have significant effects in the prevention and treatment of breast cancer.This article reviews the r...更多

Phytoestrogens are a class of natural compounds existing in plants，with their chemical structures similar to that of the endogenous estrogen 17β-estradiol in mammals.They can exert estrogenic or anti-estrogenic biological effects by binding to estrogen receptors，and have a wide range of effects on diseases caused by estrogen disorders in the body.Recent studies have discovered that phytoestrogens have significant effects in the prevention and treatment of breast cancer.This article reviews the research progress in the prevention and treatment of breast cancer with phytoestrogens from the active components of Chinese medicinal plants，Chinese medicinal plants，and traditional Chinese medicine compound formulas，as well as the related mechanisms. Specifically，the phytoestrogens exert anti-estrogenic effects by binding to estrogen receptors，regulate cell proliferation and apoptosis signaling pathways ，inhibit tumor angiogenesis，and modulate metabolism and immune function.The review aims to provide a theoretical basis for clinical research on the prevention and treatment of breast cancer with traditional Chinese medicine.收起

文献类型

期刊