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作者

Bowen Li MD Yan Gao MD Jian Wang MD Runze Zhu MD Shifeng Yang MD, PhD Congshan Ji MD, PhD Ying Wang MD Ximing Wang MD, PhD Hui Gu MD, PhD

作者单位

⁴Department of Radiology, Central Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China (J.W.) ¹Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan Shandong 250117, China (B.L., R.Z.) ³Department of Radiology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong 250021, China (Y.G., X.W., H.G.) ²Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China (B.L., Y.G., R.Z., S.Y., C.J., Y.W., X.W., H.G.)

刊名

Academic Radiology

年份

2024

ISSN

1076-6332

摘要

Rationale and Objectives The aim of the present retrospective study was to evaluate the prognostic role of the extracellular volume fraction in patients with myocardial infarction and myocardial infarction with nonobstructive coronary arteries . The present study hypothesized that ECV is associated with major adverse cardiovascular events in MI and MINOCA patients. Materials and Methods Cardiac magnetic resonance imaging was performed on 351 consecutive patients who were diagnosed with MI b...更多

Rationale and Objectives The aim of the present retrospective study was to evaluate the prognostic role of the extracellular volume fraction in patients with myocardial infarction and myocardial infarction with nonobstructive coronary arteries . The present study hypothesized that ECV is associated with major adverse cardiovascular events in MI and MINOCA patients. Materials and Methods Cardiac magnetic resonance imaging was performed on 351 consecutive patients who were diagnosed with MI between October 2015 and November 2023. From CMR imaging, the extent of late gadolinium enhancement , native T1 and ECV were derived. Patients were categorized into groups according to the degree of coronary artery stenosis, namely, patients with MINOCA and patients with obstructive MI. Follow-up was performed to assess MACEs. Results The final cohort consisted of 61 MINOCA patients and 290 obstructive MI patients. During a mean follow-up of 27 ± 16 months, there was no statistically significant difference in the incidence of MACEs between patients with MINOCA and those with obstructive MI, and the two groups of patients had similar ECVs . According to the multivariate Cox regression, ECV was an independent predictor of MACEs and significantly improved the prognostic value of the baseline multivariate models . Similarly, ECV maintained an independent association with MACEs in the MINOCA and obstructive MI groups. Conclusion In MI and MINOCA patients, ECV is an independent predictor of MACEs. MINOCA is not a benign disease, and its long-term prognosis is as poor as that of patients with obstructive MI.收起

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