获取途径

作者

Chunyan Luo Jingyang Zhang Xiaorao Wang Yu Dai Lei Yan & …Yanbo Du

作者单位

⁵Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, 250012, Shandong, China ⁴Shandong Technology Innovation Center for Reproductive Health, Jinan, 250012, Shandong, China ⁹Reproductive Hospital Affiliated to Shandong University, No.157, Jingliu Road, Shizhong District, Jinan, 250012, Shandong, China ⁸Shenzhen Maternity and Child Healthcare Hospital, Shenzhen, China ³Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, 250012, Shandong, China ¹State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, 250012, China ²National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, 250012, Shandong, China ⁷Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, 250012, Shandong, China ⁶Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250012, China

刊名

Reproductive Sciences

年份

2025

卷号

Vol.32 No.4

页码

1362-1371

ISSN

1933-7191

关键词

Premature ovulation In vitro oocyte maturation Embryo cryopreservation Window of implantation

摘要

There is limited clinical research investigating the optimal transplantation strategy in early oocyte retrieval cycles. We aimed to assess whether the maturation of oocytes from early oocyte retrieval influenced pregnancy outcomes, and to find the optimal embryo transfer strategy for patients who had early oocyte retrieval and underwent in vitro maturation . A retrospective cohort study was conducted in a university-based reproductive medical center. A total of 234 women who underwent single em...更多

There is limited clinical research investigating the optimal transplantation strategy in early oocyte retrieval cycles. We aimed to assess whether the maturation of oocytes from early oocyte retrieval influenced pregnancy outcomes, and to find the optimal embryo transfer strategy for patients who had early oocyte retrieval and underwent in vitro maturation . A retrospective cohort study was conducted in a university-based reproductive medical center. A total of 234 women who underwent single embryo transfer after early oocyte retrieval were included. The primary outcome was live birth rate. The live birth rate was significantly lower in IVM cycles compared with no IVM cycles. There was a significant decrease in live birth and a markedly elevated early pregnancy loss rate for IVM fresh cycles compared with no IVM fresh cycles. However, these findings were not repeated in subgroup analysis when frozen-thaw embryos were transferred. These results indicate that patients who underwent early oocyte retrieval and then IVM-intracytoplasmic sperm injection should be recommended the embryo cryopreservation strategy. Resynchronization of the embryo and the endometrium in frozen-thaw embryo transfer cycles may optimize live birth and decrease early pregnancy loss in IVM-intracytoplasmic sperm injection cycles after early oocyte retrieval.收起

文献类型

期刊

浏览量

1