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作者

Ou, Xiaomin Yang, Zhaozhi Zhou, Xin Zhang, Ye Wang, Qifeng Yang, Pei Zhang, Wencheng Yue, Jinbo Wu, Bin Niu, Xiaoshuang Li, Yujiao

作者单位

^bDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China ^eDepartment of Radiation Oncology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, 610041, China ^jDepartment of Diagnostic Radiology, Shanghai Proton and Heavy Ion Center, Shanghai, 201321, China ^hDepartment of Abdominal Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, 250117, China ^dProfessional Committee of Radiation Oncology, Chinese Medicine Education Association (CMEA), Changsha, 410013, China ^aDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China ^gDepartment of Radiation Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin, 300060, China ^cDepartment of Radiation Oncology, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100021, China ⁱDepartment of Diagnostic Radiology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China ^fDepartment of Radiation Oncology, Hunan Cancer Hospital, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, China

刊名

Chinese Journal of Radiation Oncology

年份

2026

卷号

Vol.35 No.3

页码

213-222

ISSN

1004-4221

关键词

Brain metastases Cerebral radiation necrosis Head and neck neoplasms Intensity-modulated radiotherapy Radiation-induced brain injury Stereotactic radiosurgery Stereotactic radiotherapy Temporal lobe necrosis

摘要

As one of the primary treatment modalities for malignant tumors, radiotherapy is widely applied in the comprehensive treatment of head and neck neoplasms and brain metastases. With advancements in radiotherapy technology, the quality of life of patients has become an important criterion for evaluating radiotherapy efficacy, second only to survival rate, and radiation-induced injury has attracted increasing attention. Radiation-induced brain injury or cerebral radiation necrosis is a common comp...更多

As one of the primary treatment modalities for malignant tumors, radiotherapy is widely applied in the comprehensive treatment of head and neck neoplasms and brain metastases. With advancements in radiotherapy technology, the quality of life of patients has become an important criterion for evaluating radiotherapy efficacy, second only to survival rate, and radiation-induced injury has attracted increasing attention. Radiation-induced brain injury or cerebral radiation necrosis is a common complication in intensity-modulated radiotherapy for head and neck neoplasms and stereotactic radiotherapy for brain metastases, seriously affecting patients' quality of life. This paper systematically summarizes current dosimetric recommendations for IMRT and SRT, and details the risk factors, imaging diagnostic principles, and treatment modalities for radiation-induced brain injury, aiming to provide a reference for the prevention, diagnosis, and treatment of CRN.收起

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